Dosimetric intercomparison of permanent Ho-166 seed's implants and HDR Ir-192 brachytherapy in breast cancer

Balloon-based adjuvant radiotherapy in breast cancer: comparison between (99m)Tc and HDR (192)Ir.

OBJECTIVE To perform a comparative dosimetric analysis, based on computer simulations, of temporary balloon implants with (99m)Tc and balloon brachytherapy with high-dose-rate (HDR) (192)Ir, as boosts to radiotherapy. We hypothesized that the two techniques would produce equivalent doses under pre-established conditions of activity and exposure time. MATERIALS AND METHODS Simulations of impla...

Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer

PURPOSE To evaluate whether Co-60 is equivalent to Ir-192 for HDR cervical brachytherapy, through 3D-DVH dose comparisons in standard and optimised plans. Previous studies have only considered 2D dosimetry, point dose comparisons or identical loading. Typical treatment times and economics are considered. MATERIAL AND METHODS Plans were produced for eight cervix patients using Co-60 and Ir-192...

Ir-192 Calibration in Air with Farmer Chamber for HDR Brachytherapy

A comprehensive review for the in-air calibration of an Ir-192 high-dose-rate brachytherapy source in terms of air kerma strength (AKS) and reference air kerma rate (RAKR) using the Farmer chamber was conducted. The reviewed calibration methods include the National Physical Laboratory (NPL) calibration standard in the UK, the 7-distance technique with the standard calibration of the National In...

A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source

Dose distributions of (192)Ir HDR brachytherapy in phantoms simulating water, bone, lung tissue, water-lung and bone-lung interfaces using the Monte Carlo codes EGS4, FLUKA and MCNP4C are reported. Experiments were designed to gather point dose measurements to verify the Monte Carlo results using Gafchromic film, radiophotoluminescent glass dosimeter, solid water, bone, and lung phantom. The re...

Breast Implants and Breast Cancer